IL7R alpha (IL7R) Rabbit Polyclonal Antibody

CAT#: TA314073

Rabbit polyclonal IL-7R/CD127 (Tyr449) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HeLa cells, using IL-7R/CD127 (Phospho-Tyr449) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunofluorescence analysis of HUVEC cells, using IL-7R/CD127 (Phospho-Tyr449) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1:500~1:3000, IF: 1:100~1:500, ELISA: 1:5000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IL-7R/CD127 around the phosphorylation site of tyrosine 449 (E-A-YP-V-T).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 7 receptor
• Database Link:
  NP_002176
  Entrez Gene 16197 MouseEntrez Gene 3575 Human
  UniProt ID P16871
• Synonyms: CD127; CDW127; IL-7R-alpha; IL7RA; ILRA
• Note: IL-7R/CD127 (Phospho-Tyr449) antibody detects endogenous levels of IL-7R/CD127 only when phosphorylated at tyrosine 449.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Primary immunodeficiency