Integrin beta 4 (ITGB4) Rabbit Polyclonal Antibody

CAT#: TA314097

Rabbit polyclonal ITGB4 (Tyr1510) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HepG2 cells, treated with Na2VO3 (0.3nM, 40mins), using ITGB4 (Phospho-Tyr1510) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:10000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-YP-S-T).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit beta 4
• Database Link:
  NP_000204
  Entrez Gene 25724 RatEntrez Gene 192897 MouseEntrez Gene 3691 Human
  UniProt ID P16144
• Synonyms: CD104; GP150
• Note: ITGB4 (Phospho-Tyr1510) antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton