JAK1 Rabbit Polyclonal Antibody

CAT#: TA314109

Rabbit polyclonal JAK1 (Tyr1022) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from A549 cells, using JAK1 (Phospho-Tyr1022) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from 3T3 cells (Lane 2), using JAK1 (Phospho-Tyr1022) Antibody. The lane on the left is treated with synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using JAK1 (Phospho-Tyr1022) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:10000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human JAK1 around the phosphorylation site of tyrosine 1022 (K-E-YP-Y-T).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Janus kinase 1
• Database Link:
  NP_002218
  Entrez Gene 16451 MouseEntrez Gene 3716 Human
  UniProt ID P23458
• Synonyms: JAK1A; JAK1B; JTK3
• Note: JAK1 (Phospho-Tyr1022) antibody detects endogenous levels of JAK1 only when phosphorylated at tyrosine 1022.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer