Rb (RB1) Rabbit Polyclonal Antibody

CAT#: TA314432

Rabbit polyclonal Retinoblastoma (Ser608) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from Jurkat cells, treated with PMA (125ng/ml, 30mins), using Retinoblastoma (Phospho-Ser608) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody. The lane on the left is treated with synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:40000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Retinoblastoma around the phosphorylation site of serine 608 (Y-L-SP-P-V).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: RB transcriptional corepressor 1
• Database Link:
  NP_000312
  Entrez Gene 19645 MouseEntrez Gene 24708 RatEntrez Gene 5925 Human
  UniProt ID P06400
• Synonyms: OSRC; p105-Rb; pp110; PPP1R130; pRb; RB
• Note: Retinoblastoma (Phospho-Ser608) antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer