Cytochrome C (CYCS) Rabbit Polyclonal Antibody
Other products for "CYCS"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 0.5-4ug/ml, IP: 10-20ug/ml |
Reactivities | Bovine, Chicken, Human, Mouse, Rat, Dog |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to residues surrounding amino acid 70 of rat cytochrome c |
Formulation | 100 µg (0.2 mg/ml) affinity purified rabbit anti-Cytochrome c polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | cytochrome c, somatic |
Database Link | |
Background | Cytochrome c (m.w. 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic cytochrome c is associated with Apaf-1 and caspase-9 to activate caspase-3 and other caspases |
Synonyms | CYC; HCS; THC4 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Small cell lung cancer, Viral myocarditis |
Documents
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