SIRT4 Rabbit Polyclonal Antibody

CAT#: TA318879

Rabbit polyclonal anti-SIRT4 antibody

Product Images

Western blot analysis of SIRT4 using rat kidney tissue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 72 of rat SIRT4
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti- SIRT3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sirtuin 4
• Database Link:
  NP_036372
  Entrez Gene 75387 MouseEntrez Gene 304539 RatEntrez Gene 23409 Human
  UniProt ID Q9Y6E7
• Background: Silent information regulator (Sir2)-like family deacetylases (also known as sirtuins) are highly conserved proteins and have important roles in the regulation of metabolism, inflammation, cellular survival growth and differentiation. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase (GLUD1), and may involve in the regulation of insulin secretion.
• Synonyms: SIR2L4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors