EZH2 Rabbit Polyclonal Antibody

CAT#: TA318887

Rabbit polyclonal anti-EZH2 antibody

Product Images

Western blot analysis of Ezh2 using rat kidney tissue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide mapping to the N-terminus of rat Ezh2
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti- EZH2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
• Database Link:
  NP_001190176
  Entrez Gene 14056 MouseEntrez Gene 312299 RatEntrez Gene 2146 Human
  UniProt ID Q15910
• Background: Enhancer of zeste homolog 2 (Ezh2) is a member of the Polycomb group (PcG). The PcG proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. Enhancer of zeste homolog 2 (Ezh2) contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. Ezh2 also plays a role as primary effector and as a mediator of tumorigenesis.
• Synonyms: ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2

Reference Data

• Protein Families: Druggable Genome, Transcription Factors