RGS3 Rabbit Polyclonal Antibody

CAT#: TA318896

Rabbit polyclonal anti-RGS3 antibody

Product Images

Western blot analysis of RGS3 in transfected HEK293 cells (right lane).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1ug/ml, IP
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli-expressed human RGS3
• Formulation: 100 µg (0.2 mg/ml) protein A-purified rabbit anti-RGS3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Database Link:
  NP_066929
  Entrez Gene 5998 Human
• Background: RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Gia and Gaq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.
• Synonyms: C2PA; PDZ-RGS3; RGP3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance