FAF1 Rabbit Polyclonal Antibody

CAT#: TA318902

Rabbit polyclonal anti-FAF1 antibody

Product Images

Western blot analysis of FAF1 in rat kidney tissue extract.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4ug/ml, IP, IHC
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 640 of human FAF1
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-FAF1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fas associated factor 1
• Database Link:
  NP_572051
  Entrez Gene 14084 MouseEntrez Gene 140657 RatEntrez Gene 11124 Human
  UniProt ID Q9UNN5
• Background: FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation.
• Synonyms: CGI-03; Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; FLJ37524; hFAF1; HFAF1s; TNFRSF6-associated factor 1; UBXD12; UBX domain protein 3A; UBXN3A

Reference Data

• Protein Families: Druggable Genome