FKBP12 (FKBP1A) Rabbit Polyclonal Antibody

CAT#: TA318937

Rabbit polyclonal anti-FKBP12 antibody

Product Images

Western blot analysis of FKBP12 expression in rat kidney tissue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml, IHC: 2-10ug/ml, IP: 2-10ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 10 of mouse FKBP12
• Formulation: 100 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: FK506 binding protein 1A
• Database Link:
  NP_000792
  Entrez Gene 14225 MouseEntrez Gene 25639 RatEntrez Gene 2280 Human
  UniProt ID P62942
• Background: FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.
• Synonyms: FKBP-1A; FKBP-12; FKBP1; FKBP12; PKC12; PKCI2; PPIASE

Reference Data

• Protein Families: Druggable Genome