Dishevelled 3 (DVL3) Rabbit Polyclonal Antibody

CAT#: TA318951

Rabbit polyclonal anti-Dvl3 antibody

Product Images

Western blot analysis of Dvl3 in Jurkat cell lysate (Lane 1& 2) and 3T3 cell lysate (Lane 3).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 583 of mouse Dvl3
• Formulation: 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: dishevelled segment polarity protein 3
• Database Link:
  NP_004414
  Entrez Gene 13544 MouseEntrez Gene 303811 RatEntrez Gene 1857 Human
  UniProt ID Q92997
• Background: Dvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.
• Synonyms: DRS3

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway