Brk (PTK6) Rabbit Polyclonal Antibody

CAT#: TA318981

Rabbit polyclonal anti-PTK6 (Brk) antibody

Product Images

Western blot analysis of Brk in lysates from Jurkat cells (Lane 1, 2), 3T3 cells (Lane 3) and rat kidney (Lane 4).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein tyrosine kinase 6
• Database Link:
  NP_005966
  Entrez Gene 20459 MouseEntrez Gene 366275 RatEntrez Gene 5753 Human
  UniProt ID Q13882
• Background: Breast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.
• Synonyms: BRK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Secreted Protein