FCN1 Rabbit Polyclonal Antibody

CAT#: TA318982

Rabbit polyclonal anti-Ficolin-1 antibody

Product Images

Western blot analysis of Ficolin-1 in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 4).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 320 of rat Ficolin-1
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ficolin 1
• Database Link:
  NP_001994
  Entrez Gene 2219 Human
  UniProt ID O00602
• Background: Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mostly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface of circulating monocytes but is not present in the plasma. Ficolin-1 has a 28 aa signal sequence, an N-terminal collagen domain and a C-terminal fibrinogen-like (FBG) domain that contain a calcium binding site and a potential N-glycosylation site.
• Synonyms: FCNM

Reference Data

• Protein Families: Druggable Genome, Secreted Protein