ST14 Rabbit Polyclonal Antibody

CAT#: TA318984

Rabbit polyclonal anti-Matriptase antibody

Product Images

Western blot analysis of Matriptase expression with Jurkat cell lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 629 of rat Matriptase
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: suppression of tumorigenicity 14
• Database Link:
  NP_068813
  Entrez Gene 19143 MouseEntrez Gene 114093 RatEntrez Gene 6768 Human
  UniProt ID Q9Y5Y6
• Background: Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2, pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 (HAI-1), which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.
• Synonyms: ARCI11; HAI; MT-SP1; MTSP1; PRSS14; SNC19; TADG15; TMPRSS14

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane