Activin A Receptor Type IC (ACVR1C) Rabbit Polyclonal Antibody

CAT#: TA319010

Rabbit polyclonal anti-ACVR1C (ALK7) antibody

Product Images

Western blot analysis of ALK 7 with lysate from rat kidney tissue (Lane 1) and Jurkat cells (Lane 2 & 3).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 155 of mouse ALK-7
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: activin A receptor type 1C
• Database Link:
  NP_001104503
  Entrez Gene 245921 RatEntrez Gene 269275 MouseEntrez Gene 130399 Human
  UniProt ID Q8NER5
• Background: ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
• Synonyms: ACVRLK7; ALK7

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Adherens junction, Chronic myeloid leukemia, Colorectal cancer, Endocytosis, MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway