PDE3B Rabbit Polyclonal Antibody

CAT#: TA319015

Rabbit polyclonal anti-PDE3B antibody

Product Images

Western blot analysis of PDE3B with lysate from 3T3 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 948 of mouse PDE3B.
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: phosphodiesterase 3B
• Database Link:
  NP_000913
  Entrez Gene 18576 MouseEntrez Gene 29516 RatEntrez Gene 5140 Human
  UniProt ID Q13370
• Background: The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B. Phosphodiesterases (PDE) are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. PDE3B has two splice variants that are expressed in adipocyte tissue, hepatocyte, kidney, spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity.
• Synonyms: cGIPDE1; HcGIP1

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Insulin signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism