CCL3 Rabbit Polyclonal Antibody

CAT#: TA319049

Rabbit polyclonal anti-CCL3 (MIP-1-alpha) antibody

Product Images

Western blot analysis of MIP-1-alpha with RAW264.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml, IP: 4-8ug/ml
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli-expressed mature rat MIP-1a (a.a. 1-69)
• Formulation: 100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-rat MIP-1a polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C-C motif chemokine ligand 3
• Database Link:
  NP_002974
  Entrez Gene 6348 Human
  UniProt ID P10147
• Background: MIP-1a (macrophage inflammatory protein-1a is a 60-amino acid CC chemokine with a molecular weight of 7.9 kDa. MIP-1a induces migration of monocytes/macrophages, B-lymphocytes, activated CD8+ T cells, natural killer (NK) cells, eosinophils. MIP-1a also stimulates basophils to release histamine, induces ICAM-1 expression, mast cell degranulation, and production of TNF-a, IL-1 and IL-6. In addition to its proinflammatory activities, MIP-1a inhibits the proliferation of hematopoietic stem cells in vitro and in vivo.
• Synonyms: G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway