Pannexin 1 (PANX1) Rabbit Polyclonal Antibody

CAT#: TA319068

Rabbit polyclonal anti-PANX1 antibody (NT)

Product Images

Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-2 ug/ml, ELISA
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG1
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pannexin 1
• Database Link:
  NP_056183
  Entrez Gene 55991 MouseEntrez Gene 315435 RatEntrez Gene 24145 Human
  UniProt ID Q96RD7
• Background: The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
• Synonyms: MRS1; PX1; UNQ2529

Reference Data

• Protein Families: Transmembrane