Leptin (LEP) Rabbit Polyclonal Antibody

CAT#: TA319080

Rabbit polyclonal anti-Leptin antibody

Product Images

Western blot analysis using recombinant rat Leptin. Lane 1: 5 ng, Lane 2: 10 ng.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli-expressed recombinant rat Leptin
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: leptin
• Database Link:
  NP_000221
  Entrez Gene 25608 Rat
  UniProt ID P41159
• Background: Leptin is a recently identified protein product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding leptin have been isolated from human, simian, mouse and rat cells. The expression of leptin mRNA has been shown to be restricted to adipose tissue. Leptin plays an important role in reproduction, immunological response and neuroendocrine signaling.
• Synonyms: LEPD; OB; OBS

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction