SDF1 (CXCL12) Rabbit Polyclonal Antibody

CAT#: TA319083

Rabbit polyclonal anti-SDF-1beta antibody

Product Images

Western blot analysis of SDF-1beta expression in transfected cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000-2500, IP
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli-expressed mouse SDF-1β
• Formulation: 100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C-X-C motif chemokine ligand 12
• Database Link:
  NP_000600
  Entrez Gene 20315 MouseEntrez Gene 24772 Rat
  UniProt ID P48061
• Background: SDF-1β (stromal cell-derived factor-β), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
• Synonyms: IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration