MMP9 Rabbit Polyclonal Antibody

CAT#: TA319098

Rabbit polyclonal anti-MMP-9 antibody

Product Images

Western blot analysis of MMP-9 in the supernatant of rat MMP transfected cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml, IP: 4-8ug/ml, IHC: 20-40 ug/ml
• Reactivities: Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli-expressed active rat 92-kDa type IV collagenase
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-rat MMP-9 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 9
• Database Link:
  NP_004985
  Entrez Gene 81687 Rat
• Background: The mammalian Matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a single peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-9 (92 kDa type IV collagenase, Gelatinase-B) contains the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.
• Synonyms: CLG4B; GELB; MANDP2; MMP-9

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Bladder cancer, Leukocyte transendothelial migration, Pathways in cancer