PTCRA Rabbit Polyclonal Antibody

CAT#: TA319112

Rabbit polyclonal anti-TCR alpha antibody

Product Images

Western blot analysis of TCR-alpha expression in Jurkat cell lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml, IHC: 15-25 ug/ml, IP: 10-20 ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 138 of human TCRa
• Formulation: 100 mg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pre T-cell antigen receptor alpha
• Database Link:
  NP_612153
  Entrez Gene 19208 MouseEntrez Gene 116462 RatEntrez Gene 171558 Human
  UniProt ID Q6ISU1
• Background: TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either a and β or ? and d chains. The vast majority of circulating T cells (95%) express the a/β heterodimer while roughly 2-5% express the ?/d heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
• Synonyms: PT-ALPHA; PTA

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Notch signaling pathway