IGFBP5 Rabbit Polyclonal Antibody

CAT#: TA319122

Rabbit polyclonal anti-IGF-BP5 antibody

Product Images

Western blot analysis of IGF-BP5 using recombinant human IGFBP5.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5-4 ug/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E. coli expressed human IGF-BP5
• Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: insulin like growth factor binding protein 5
• Database Link:
  NP_000590
  Entrez Gene 3488 Human
  UniProt ID P24593
• Background: Human IGF-BP5 is a cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development.
• Synonyms: IBP5

Reference Data

• Protein Families: Druggable Genome, Secreted Protein