TORC1 (CRTC1) Rabbit Polyclonal Antibody

CAT#: TA319268

Rabbit polyclonal anti-MECT1 antibody

Product Images

WB using Anti-MECT2 antibody shows detection of MECT2 (lower arrowhead) and MECT2:MAML2 fusion protein (top arrowhead) in cell lysates. Lane 1 contains lysate from cells expressing MECT2 only. Lane 2 contains lysate from cells transfected with fusion protein. Lane 3 contains lysate from cells strongly expressing MECT2 and weakly expressing the fusion protein. Lane 4 contains lysate from control cells. Primary antibody was used at a 1:1000 dilution.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:10,000 - 1:40,000, WB: 1:500 - 1:2,000
• Reactivities: Human, Mouse, Rat, Zebrafish, Pufferfish, Bovine
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 19-34 of human MECT1 protein.
• Formulation: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CREB regulated transcription coactivator 1
• Database Link:
  NP_001091952
  Entrez Gene 382056 MouseEntrez Gene 684527 RatEntrez Gene 23373 Human
  UniProt ID Q6UUV9
• Synonyms: MECT1; TORC-1; TORC1; WAMTP1
• Note: This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1, Transducer of regulated cAMP response element-binding protein 1, TORC1, and Transducer of CREB protein 1) is a nuclear protein that functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1does not appear to modulate CREB1 DNA-binding activity but

Reference Data

• Protein Families: Transcription Factors