IL2 Rabbit Polyclonal Antibody

CAT#: TA319284

Rabbit polyclonal IL-2 antibody Peroxidase Conjugated

Product Images

Western Blot of Rabbit anti-IL-2 Antibody Peroxidase Conjugated Lane 1: Human IL-2 Recombinant Protein Load: 50 ng per lane Secondary antibody: Peroxidase Conjugated IL-2 Antibody at 1:1000 for 60 min at RT Block: MB-070 for 30 min at RT Predicted/Observed size: 16 kDa, 16 kDa

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:10,000-1:50,000, WB: 1:1,000-1:5,000, IHC: 1:500-1:2,500
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-2 protein.
• Formulation: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 2
• Database Link:
  NP_000577
  Entrez Gene 3558 Human
  UniProt ID P60568
• Synonyms: IL-2; lymphokine; TCGF
• Note: IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus