Emi1 (FBXO5) Rabbit Polyclonal Antibody
Other products for "FBXO5"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1:5,000 - 1:20,000, WB: 1:500 - 1:3,000, IHC: 1:500 - 1:3,000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminal end of human Fbp5A protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | F-box protein 5 |
Database Link | |
Synonyms | EMI1; FBX5; Fbxo31 |
Note | Fbp5A is a member of the F-box protein family that is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to Xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase-promoting complex. |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Oocyte meiosis |
Documents
Product Manuals |
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