Ppard Rabbit Polyclonal Antibody

CAT#: TA319467

Rabbit polyclonal PPAR Delta antibody

Product Images

Anti-PPAR delta to detect a predominant band at ~ 43 kDa corresponding to PPAR delta present in mouse heart whole cell lysates. Approximately 30 ug of lysate was loaded per lane for SDS-PAGE. Detection occurred using a 1:750 dilution of primary antibody overnight at 4°C followed reaction with a 1:10,000 dilution of IRDye® 800 conjugated Gt-a-Rabbit IgG (H&L) for 45 min at RT.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:600,000, WB: 1:500 - 1:5,000
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of mouse PPAR delta.
• Formulation: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: peroxisome proliferator activator receptor delta
• Database Link:
  NP_035275
  Entrez Gene 25682 RatEntrez Gene 19015 Mouse
  UniProt ID P35396
• Synonyms: FAAR; MGC3931; NR1C2; NUC1; NUCI; NUCII; OTTHUMP00000016256; OTTHUMP00000016257; PPAR-beta; PPAR-delta; PPARB
• Note: Since their discovery in the early 1990's, the peroxisome proliferator activated receptors (PPARs) have attracted significant attention. This is primarily because PPARs serve as receptors for two very important classes of drugs: the hypolipidemic fibrates and the insulin sensitizing thiazolidinediones. Peroxisome proliferators are non-genotoxic carcinogens that are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed PPARs. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Upon binding fatty acids or hypolipidemic drugs, PPARs