IL17E (IL25) Mouse Monoclonal Antibody [Clone ID: 11K8B1]

CAT#: TA319594

Mouse monoclonal IL-17E antibody

Product Images

Western Blot of Mouse anti-IL-17E antibody in full length recombinant protein using IL-17E antibody at 0.5 ug/ml.

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  Flow Cytometry of Mouse anti-IL-17E antibody Cells: PC3 cells Primary antibody: 1 ug of IL-17E (red), control (green) Secondary antibody: anti-mouse IgG PE conjugated secondary antibody.

Specifications

Product Data

• Clone Name: 11K8B1
• Applications: FC, WB
• Recommended Dilution: WB: 0.5ug/mL, FC: 1ug/mL
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
• Formulation: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 25
• Database Link:
  NP_073626
  Entrez Gene 64806 Human
  UniProt ID Q9H293
• Synonyms: IL17E
• Note: Anti-IL17E recognizes IL-17E (also known as IL25). IL-17E is produced and secreted by intra-epithelial lymphocytes, lung epithelial cells, alveolar macrophages, eosinophils, basophils, NKT cells, mast cells and cells of the gastro-intestinal tract and uterus. IL-17E stimulates the production of Th2-type cytokines. IL-17E limits Th17 cell development by inducing the expression of IL-13 by dendritic cells or by inhibiting IL-23 production by macrophages. Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. A number of cytokines, including IL-17E, have been implicated as oncogenes, reflecting the importance of these proteins in cell growth and survival. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and pro-inflammatory pathologies.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction