Ido2 Mouse Monoclonal Antibody [Clone ID: 1HC]

CAT#: TA319602

Mouse monoclonal anti-IDO2 antibody

Product Images

Western Blot of Mouse Anti-IDO2 antibody. Lane 1: HEK293 no transgene cell extracts. Lane 2: mouse IDO-2 transgene expressed in 293HEK. Lane 3: mouse IDO-1 transgene expressed in 293HEK. Primary antibody: IDO2 monoclonal Antibody. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 44.4 kDa, ~60 kDa for IDO 2. Other band (s): IDO2 splice variants and isoforms.

Specifications

Product Data

• Clone Name: 1HC
• Applications: WB
• Recommended Dilution: ELISA: 1:5000-1:50000, WB: 1:500-1:1500, IF: 1:50-1:100
• Reactivities: Mouse
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Anti-IDO2 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with complete mouse IDO2 protein followed by hybridoma development.
• Formulation: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: indoleamine 2,3-dioxygenase 2
• Database Link:
  NP_666061
  Entrez Gene 209176 Mouse
  UniProt ID Q8R0V5
• Synonyms: INDOL1
• Note: Indoleamine 2,3-dioxygenase 2 (IDO2) is related to IDO1, and may play a role in T and B Cell Immunity. IDO2’s role in immune regulation will be become clearer following the completion of genetic knock-out studies. IDO2 is expressed in a few select cell types and levels of protein expression appear to be very low, perhaps below the level of detection by IHC. Small-molecule inhibitors of indoleamine 2,3-dioxygenase (IDO) are currently being translated to clinic for evaluation as cancer therapeutics.