Angiogenin (ANG) Rabbit Polyclonal Antibody

CAT#: TA319609

Rabbit Polyclonal ANG Antibody

Product Images

Western blot analysis of ANG in rat liver tissue lysate with Ang antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of ANG in human liver tissue with ANG antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG.
• Formulation: ANG Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ANG Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 16 kDa
• Gene Name: angiogenin
• Database Link:
  NP_001091046
  Entrez Gene 11727 MouseEntrez Gene 305843 RatEntrez Gene 283 Human
  UniProt ID P03950
• Background: ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
• Synonyms: ALS9; HEL168; RAA1; RNASE4; RNASE5

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane