Angiopoietin 2 (ANGPT2) Rabbit Polyclonal Antibody

CAT#: TA319610

Rabbit Polyclonal ANGPT2 Antibody

Product Images

Western blot analysis of ANGPT2 in human liver tissue lysate with ANGPT2 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of ANGPT2 in mouse liver tissue with ANGPT2 antibody at 2.5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ANGPT2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ANGPT2.
• Formulation: ANGPT2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ANGPT2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: angiopoietin 2
• Database Link:
  NP_001138
  Entrez Gene 11601 MouseEntrez Gene 89805 RatEntrez Gene 285 Human
  UniProt ID O15123
• Background: ANGPT2 Antibody: Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers.
• Synonyms: AGPT2; ANG2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein