Claudin 4 (CLDN4) Rabbit Polyclonal Antibody

CAT#: TA319632

Rabbit Polyclonal CLAUDIN4 Antibody

Product Images

Western blot analysis of CLAUDIN4 in human colon tissue lysate with CLAUDIN4 antibody at 1 ug/ml

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  Immunofluorescence of CLAUDIN4 in human colon tissue with CLAUDIN4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CLAUDIN4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4.
• Formulation: CLAUDIN4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: CLAUDIN4 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: claudin 4
• Database Link:
  NP_001296
  Entrez Gene 12740 MouseEntrez Gene 304407 RatEntrez Gene 1364 Human
  UniProt ID O14493
• Background: CLAUDIN4 Antibody: CLAUDIN4 is an integral membrane protein belonging to the claudin family, a family of cellular adhesion molecules that are components of tight junctions. CLAUDIN4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The CLAUDIN4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. CLAUDIN4 is frequently overexpressed in ovarian and other epithelial cancers.
• Synonyms: CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction