EZH1 Rabbit Polyclonal Antibody

CAT#: TA319647

Rabbit Polyclonal EZH1 Antibody

Product Images

Western blot analysis of EZH1 in mouse lung tissue lysate with EZH1 antibody at (A) 1 and (B) 2 ug/mL

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  Immunohistochemistry of EZH1 in human lung tissue with EZH1 antibody at 5 ug/mL.

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  Immunofluorescence of EZH1 in human lung tissue with EZH1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: EZH1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EZH1.
• Formulation: EZH1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: EZH1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
• Database Link:
  NP_001982
  Entrez Gene 14055 MouseEntrez Gene 303547 RatEntrez Gene 2145 Human
  UniProt ID Q92800
• Background: EZH1 Antibody: EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair.
• Synonyms: KMT6B

Reference Data

• Protein Families: Druggable Genome, Transcription Factors