GDF1 Rabbit Polyclonal Antibody

CAT#: TA319656

Rabbit Polyclonal GDF1 Antibody

Product Images

Western blot analysis of GDF1 in rat lung tissue lysate with GDF1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunofluorescence of GDF1 in human lung tissue with GDF1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal GDF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human GDF1.
• Formulation: GDF1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: GDF1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41 kDa
• Gene Name: growth differentiation factor 1
• Database Link:
  NP_001483
  Entrez Gene 14559 MouseEntrez Gene 306351 RatEntrez Gene 2657 Human
  UniProt ID P27539
• Background: GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
• Synonyms: DORV; DTGA3; RAI

Reference Data

• Protein Families: Druggable Genome, Secreted Protein