Nucleobindin 2 (NUCB2) Rabbit Polyclonal Antibody

CAT#: TA319691

Rabbit Polyclonal Nucleobindin-2 Antibody

Product Images

Western blot analysis of Nucleobindin-2 in rat brain tissue lysate with Nucleobindin-2 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunohistochemistry of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 2.5 ug/mL.

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  Immunofluorescence of Nucleobindin-2 in rat brain tissue with Nucleobindin-2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Nucleobindin-2 antibody was raised against a 16 amino acid peptide near the center of human Nucleobindin-2 .
• Formulation: Nucleobindin-2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Nucleobindin-2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 46 kDa; Observed: 54 kDa
• Gene Name: nucleobindin 2
• Database Link:
  NP_005004
  Entrez Gene 53322 MouseEntrez Gene 59295 RatEntrez Gene 4925 Human
  UniProt ID P80303
• Background: Nucleobindin-2 Antibody: NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
• Synonyms: HEL-S-109; NEFA

Reference Data

• Protein Families: Secreted Protein, Transmembrane