DPF2 Rabbit Polyclonal Antibody

CAT#: TA319699

Rabbit Polyclonal REQUIEM Antibody

Product Images

Western blot analysis of Requiem in mouse kidney tissue lysate with Requiem antibody at 1 ug/mL.

• 

  Immunohistochemistry of REQUIEM in human kidney tissue with REQUIEM antibody at 5 ug/mL.

• 

  Immunofluorescence of REQUIEM in human kidney tissue with REQUIEM antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: REQUIEM antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human Requiem.
• Formulation: REQUIEM Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: REQUIEM Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: double PHD fingers 2
• Database Link:
  NP_006259
  Entrez Gene 19708 MouseEntrez Gene 5977 Human
  UniProt ID Q92785
• Background: REQUIEM Antibody: Requiem is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It is expressed in numerous tissues in both cytosolic and nuclear regions and likely serves a regulatory role in rapid hematopoietic cell growth and turnover. Requiem has been found to act as an adaptor protein that links the NF-κB and SWI/SNF chromatin remodeling factor and is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
• Synonyms: REQ; ubi-d4; UBID4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors