TARC (CCL17) Rabbit Polyclonal Antibody

CAT#: TA319703

Rabbit Polyclonal CCL17 Antibody

Product Images

Western blot analysis of CCL17 in rat spleen tissue lysate with CCL17 antibody at (A) 1 and (B) 2 ug/mL

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  Immunohistochemistry of CCL17 in spleen tissue with CCL17 antibody at 5 ug/mL.

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  Immunofluorescence of CCL17 in human spleen tissue with CCL17 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Rabbit polyclonal CCL17 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CCL17.
• Formulation: CCL17 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: CCL17 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 10 kDa
• Gene Name: C-C motif chemokine ligand 17
• Database Link:
  NP_002978
  Entrez Gene 20295 MouseEntrez Gene 117518 RatEntrez Gene 6361 Human
  UniProt ID Q92583
• Background: CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.
• Synonyms: A-152E5.3; ABCD-2; SCYA17; TARC

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction