SGK1 Rabbit Polyclonal Antibody

CAT#: TA319704

Rabbit Polyclonal SGK1 Antibody

Product Images

Western blot analysis of SGK1 in human stomach tissue lysate with SGK1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of SGK1 in human stomach tissue with SGK1 antibody at 5 ug/mL.

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  Immunofluorescence of SGK1 in human stomach tissue with SGK1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SGK1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SGK1.
• Formulation: SGK1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SGK1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: serum/glucocorticoid regulated kinase 1
• Database Link:
  NP_001137148
  Entrez Gene 20393 MouseEntrez Gene 29517 RatEntrez Gene 6446 Human
  UniProt ID O00141
• Background: SGK1 Antibody: Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
• Synonyms: SGK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase