SIPA1 Rabbit Polyclonal Antibody

CAT#: TA319705

Rabbit Polyclonal SIPA1 Antibody

Product Images

Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 ug/mL.

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  Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1.
• Formulation: SIPA1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SIPA1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: signal-induced proliferation-associated 1
• Database Link:
  NP_006738
  Entrez Gene 6494 Human
  UniProt ID Q96FS4
• Background: SIPA1 Antibody: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.
• Synonyms: SPA1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Leukocyte transendothelial migration