SPINK2 Rabbit Polyclonal Antibody

CAT#: TA319708

Rabbit Polyclonal SPINK2 Antibody

Product Images

Western blot analysis of SPINK2 in mouse heart tissue lysate with SPINK2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

• 

  Immunohistochemistry of SPINK2 in mouse testis tissue with SPINK2 antibody at 2.5 ug/mL.

• 

  Immunofluorescence of SPINK2 in mouse testis tissue with SPINK2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SPINK2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human SPINK2.
• Formulation: SPINK2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SPINK2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: serine peptidase inhibitor, Kazal type 2
• Database Link:
  NP_066937
  Entrez Gene 69982 MouseEntrez Gene 6691 Human
  UniProt ID P20155
• Background: SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.
• Synonyms: HUSI-II

Reference Data

• Protein Families: Secreted Protein, Transmembrane