Trefoil Factor 3 (TFF3) Rabbit Polyclonal Antibody

CAT#: TA319717

Rabbit Polyclonal TFF3 Antibody

Product Images

Western blot analysis of TFF3 in human colon tissue lysate with TFF3 antibody at 1ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of TFF3 in human small intestine tissue with TFF3 antibody at 2ug/ml.

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  Immunohistochemistry of TFF3 in human small intestine tissue with TFF3 antibody at 2.5ug/ml.

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  Immunofluorescence of TFF3 in Human Small Intestine tissue with TFF3 antibody at 20ug/ml.

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  Immunocytochemistry of TFF3 in HeLa cells with TFF3 antibody at 2ug/ml.

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  Immunofluorescence of TFF3 in human small intestine tissue with TFF3 antibody at 20ug/ml.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TFF3 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human TFF3. The immunogen is located within the last 50 amino acids of TFF3.
• Formulation: TFF3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TFF3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: trefoil factor 3
• Database Link:
  NP_003217
  Entrez Gene 21786 MouseEntrez Gene 25563 RatEntrez Gene 7033 Human
  UniProt ID Q07654
• Background: TFF3 Antibody: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
• Synonyms: ITF; P1B; TFI

Reference Data

• Protein Families: Secreted Protein