Translin (TSN) Rabbit Polyclonal Antibody

CAT#: TA319727

Rabbit Polyclonal Translin Antibody

Product Images

Western blot analysis of Translin in rat lung tissue lysate with Translin antibody at (A) 0.5 and (B) 1 ug/mL

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  Immunohistochemistry of Translin in human lung tissue with Translin antibody at 5 ug/mL.

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  Immunofluorescence of Translin in human lung tissue with Translin antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.
• Formulation: Translin Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Translin Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: translin
• Database Link:
  NP_004613
  Entrez Gene 22099 MouseEntrez Gene 60381 RatEntrez Gene 7247 Human
  UniProt ID Q15631
• Background: Translin Antibody: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
• Synonyms: BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN