TFEB Rabbit Polyclonal Antibody

CAT#: TA319741

Rabbit Polyclonal TFEB Antibody

Product Images

Western blot analysis of TFEB in A549 cell lysate with TFEB antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of TFEB (NT) in human lung tissue with TFEB (NT) antibody at 2.5 ug/mL.

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  Immunofluorescence of TFEB in human lung tissue with TFEB antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TFEB antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TFEB.
• Formulation: TFEB Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TFEB Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transcription factor EB
• Database Link:
  NP_001161299
  Entrez Gene 7942 Human
  UniProt ID P19484
• Background: TFEB Antibody: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
• Synonyms: ALPHATFEB; BHLHE35; TCFEB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors