EPM2A Rabbit Polyclonal Antibody

CAT#: TA319742

Rabbit Polyclonal EPM2A Antibody

Product Images

Western blot analysis of SW480 in SW480 cell lysate with EPM2A antibody at (A) 1 and (B) 2 ug/mL.

• 

  Immunocytochemistry of EPM2A in SW480 cells with EPM2A antibody at 2.5 ug/mL.

• 

  Immunofluorescence of EPM2A in SW480 cells with EPM2A antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A.
• Formulation: EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: EPM2A Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
• Database Link:
  NP_005661
  Entrez Gene 13853 MouseEntrez Gene 114005 RatEntrez Gene 7957 Human
  UniProt ID O95278
• Background: EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
• Synonyms: EPM2; MELF

Reference Data

• Protein Families: Druggable Genome, Phosphatase