Axin 1 (AXIN1) Rabbit Polyclonal Antibody

CAT#: TA319744

Rabbit Polyclonal AXIN1 Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen AXIN1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human AXIN1.
Formulation AXIN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification AXIN1 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name axin 1
Background AXIN1 Antibody: AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.
Synonyms AXIN; PPP1R49
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Wnt signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.