BCAR3 Rabbit Polyclonal Antibody

CAT#: TA319747

Rabbit Polyclonal BCAR3 Antibody

Product Images

Western blot analysis of BCAR3 in mouse kidney tissue lysate with BCAR3 antibody at A) 1 and (B) 2 ug/mL.

• 

  Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3.
• Formulation: BCAR3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: BCAR3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 91 kDa
• Gene Name: breast cancer anti-estrogen resistance 3
• Database Link:
  NP_001248337
  Entrez Gene 29815 MouseEntrez Gene 310838 RatEntrez Gene 8412 Human
  UniProt ID O75815
• Background: BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
• Synonyms: NSP2; SH2D3B

Reference Data

• Protein Families: Druggable Genome