BCAR3 Rabbit Polyclonal Antibody
Other products for "BCAR3"
Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 1 - 2 ug/mL, IF: 20 ug/mL |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3. |
Formulation | BCAR3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | BCAR3 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 91 kDa |
Gene Name | breast cancer anti-estrogen resistance 3 |
Database Link | |
Background | BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling. |
Synonyms | NSP2; SH2D3B |
Reference Data | |
Protein Families | Druggable Genome |
Documents
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