IFITM1 Rabbit Polyclonal Antibody

CAT#: TA319752

Rabbit Polyclonal IFITM1 Antibody

Product Images

Western blot analysis of IFITM1 in 3T3 cell lysate with IFITM1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunocytochemistry of IFITM1 in Jurkat cells with IFITM1 antibody at 20 ug/mL.

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  Immunofluorescence of IFITM1 in Jurkat cells with IFITM1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 20 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: IFITM1 antibody was raised against a 16 amino acid synthetic peptide near the center of human IFITM1.
• Formulation: IFITM1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: IFITM1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interferon induced transmembrane protein 1
• Database Link:
  NP_003632
  Entrez Gene 68713 MouseEntrez Gene 293618 RatEntrez Gene 8519 Human
  UniProt ID P13164
• Background: IFITM1 Antibody: IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
• Synonyms: 9-27; CD225; DSPA2a; IFI17; LEU13

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: B cell receptor signaling pathway