TIF1 alpha (TRIM24) Rabbit Polyclonal Antibody

CAT#: TA319761

Rabbit Polyclonal TRIM24 Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24.
Formulation TRIM24 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification TRIM24 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 112 kDa
Gene Name tripartite motif containing 24
Background TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).
Synonyms hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.