ROCK2 Rabbit Polyclonal Antibody

CAT#: TA319779

Rabbit Polyclonal ROCK2 Antibody

Product Images

Western blot analysis of ROCK2 in mouse brain tissue lysate with ROCK2 antibody at (A) 1 and (B) 2 ug/mL

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  Immunohistochemistry of ROCK2 in mouse brain tissue with ROCK2 antibody at 5 ug/mL.

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  Immunofluorescence of ROCK2 in mouse brain tissue with ROCK2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ROCK2 antibody was raised against a 15 amino acid synthetic peptide near the center of human ROCK2.
• Formulation: ROCK2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: ROCK2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Rho associated coiled-coil containing protein kinase 2
• Database Link:
  NP_004841
  Entrez Gene 19878 MouseEntrez Gene 25537 RatEntrez Gene 9475 Human
  UniProt ID O75116
• Background: ROCK2 Antibody: ROCK2 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK2 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK2, like its isozyme ROCK1, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.
• Synonyms: ROCK-II

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, TGF-beta signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway