UBA2 Rabbit Polyclonal Antibody

CAT#: TA319807

Rabbit Polyclonal SAE2 Antibody

Product Images

Western blot analysis of SAE2 in 293 cell lysate with SAE2 antibody at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of SAE2 in 293 cells with SAE2 antibody at 20 ug/mL.

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  Immunocytochemistry of SAE2 in 293 cells with SAE2 antibody at 4 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.25 ug/mL, ICC:4 ug/mL, IF: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SAE2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SAE2.
• Formulation: SAE2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SAE2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ubiquitin like modifier activating enzyme 2
• Database Link:
  NP_005490
  Entrez Gene 10054 Human
  UniProt ID Q9UBT2
• Background: SAE2 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
• Synonyms: ARX; HRIHFB2115; SAE2

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis